Multidrug-resistant tuberculosis (MDR-TB) is a major threat to global TB control. MDR-TB treatment regimens typically last 20 months or more, require a patient to take a high number of pills, and often lead to unsatisfactory

Artemisinin-resistant Plasmodium falciparum malaria parasites are now present across much of mainland Southeast Asia, where ongoing surveys are measuring and mapping their spatial distribution. These efforts require substantial resources. Here we propose a generic ‘smart

During a cholera outbreak in May 2015, in Juba, South Sudan, the Ministry of Health, Doctors Without Borders/Médecins Sans Frontières (MSF) and partners engaged in the first field deployment of a single dose of oral cholera

Antibiotic stewardship program (ASP) implementation in humanitarian settings is a new endeavour – Doctors Without Borders/Médecins Sans Frontières (MSF) introduced an ASP within a hospital in Amman, Jordan, where patients from Iraq, Syria, and Yemen

In Afghanistan, Doctors Without Borders/Médecins Sans Frontières (MSF) provided specialised trauma care in Kunduz Trauma Centre (KTC), including physiotherapy. In this study, we describe the development of an adapted functional score for patient outcome monitoring

Today’s global market has multiple standards. Patients in low- and middle-income countries often receive poor-quality medicines. Despite increasing awareness about the issue and the launch of some initiatives, the divide in quality of pharmaceuticals between

Multidrug-resistant tuberculosis (MDR-TB) is a major threat to global TB control. MDR-TB treatment regimens typically have a high pill burden, last 20 months or more and often lead to unsatisfactory outcomes. A 9–11 month regimen

Collaborative clinical research that addresses the health needs of low and middle-income countries (LMICs) has become more frequent recently. Such research includes therapeutic and diagnostic trials for neglected tropical diseases (NTDs), and is often conducted

Trauma is one of the leading causes of death in developing countries – where there is limited access to good quality emergency care. Doctors Without Borders/Médecins Sans Frontières (MSF) delivered a standard package of care

The Doctors Without Borders/Médecins Sans Frontières (MSF) ethics review board (ERB) was solicited in an unprecedented way to provide advice and review research protocols in an ‘emergency’ mode during the recent Ebola epidemic. Twenty-seven Ebola-related

Multidrug-resistant tuberculosis (MDR TB), is a significant threat to TB control efforts. Previous prevailing views that resistance was mainly acquired through poor treatment led to decades of focus on drug-sensitive rather than drug-resistant (DR) TB.

This study assesses the feasibility and added value of using the Xpert Ebola Assay in an Ebola control program in Guinea. Several logistic and safety issues were identified and the study suggests that implementation of